PROVARX

Nutraceutical Manufacturing

21 CFR Part 111 cGMP compliance software for dietary supplement manufacturers

Identity testing, lot traceability, and batch formula version control — Provarx gives nutraceutical manufacturers the documentation infrastructure to survive FDA scrutiny.

$11M
average cost of a dietary supplement recall
SOC 2 Type IIFDA 21 CFR Part 11Blockchain-verifiedFSMA 204 Ready

Regulations this page addresses

cGMP for Dietary Supplements · 21 CFR Part 111DSHEA · Dietary Supplement Health and Education ActIdentity Testing Requirements · 21 CFR 111.75Label Claim Substantiation · FTC Act Section 5Supplier Verification · 21 CFR 111.475

The Problem

Why compliance fails in nutraceutical manufacturing facilities

FDA warning letter risk

FDA warning letters to supplement companies almost always cite batch record deficiencies — the documentation gap is the most common enforcement trigger.

COA tracking chaos

Certificate of Analysis tracking across multiple ingredient suppliers is chaotic — missing COAs create identity testing gaps that fail 21 CFR Part 111.

Formula versioning failures

Knowing which lot used which version of a formula is critical under cGMP — and it's rarely documented in a way that survives an inspection.

Cross-system recall traceability

Recall traceability by lot requires cross-referencing records that live in three different systems — creating costly delays and compliance gaps.

The Solution

How Provarx solves it

COA tracking per ingredient lot

Every ingredient lot is linked to its COA at receiving — creating an unbroken chain from supplier certificate to finished product batch.

Before Provarx
COAs stored in email threads, disconnected from batches
After Provarx
COA linked to every lot at receiving, searchable instantly

Formula versioning with audit trail

Every batch is locked to the exact formula version used — creating a tamper-proof record of what was manufactured and when.

Before Provarx
Shared spreadsheet formulas with no version history
After Provarx
Immutable formula-to-lot linkage with approval trail

Identity test documentation per batch

Identity testing results are captured per batch with test method, result, and sign-off — meeting 21 CFR 111.75 requirements precisely.

Before Provarx
Identity test results logged informally or not at all
After Provarx
Structured identity test records linked to each batch

Lot-level recall trace

Trace any recall across finished product, components, and supplier lots — from a single query, in under 60 seconds.

Before Provarx
Days cross-referencing three disconnected systems
After Provarx
60-second end-to-end lot trace, single system

Results

“I built Provarx because I lived the problem. I've stood on production floors, prepped for FDA audits at 6am, and watched facilities scramble to reconstruct records that should have been one click away.”

Clinton — Founder, Provarx · Six Sigma Black Belt · OSHA 30 · 10+ years regulated manufacturing

Ready to make your nutraceutical manufacturing operation audit-proof?

No enterprise contracts. No six-month implementations. A platform built for the specific regulations your facility operates under — and the audits you actually face.